Last Revised - 09/15/2019. Make sure laboratory personnel and all your doctors know you use this drug. May also be prescribed off label for Esophageal Spasm. There are 195 drugs known to interact with This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If this worries you, talk to your doctor or pharmacist about other options. the unsubscribe link in the e-mail. This content does not have an English version. Some side effects may occur that usually do not need medical attention. Other medications may be prescribed by your doctor for these conditions. Prices for isosorbide mononitrate (Monoket) start at just $29.86 with a GoodRx coupon. Headache and weakness of left side (both arm and leg) may suggest a brain pathology. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). information and will only use or disclose that information as set forth in our notice of The most common side-effect is headache. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Treatment and prognosis of heart failure with preserved ejection . Some conditions may become worse when the drug is suddenly stopped. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Do not double the dose to catch up. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. This site needs JavaScript to work properly. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Isosorbide dinitrate dose 30-120 mg daily in divided doses. Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. The extended-release tablet usually is taken once daily in the morning. All rights reserved. Try our Symptom Checker Got any other symptoms? Review/update the You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Prescribed for Angina, Anal Fissure and Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. You can take your doses either before or after meals. My cardiologist recommended I get on metropolol. PMC Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. It is not intended as medical advice for individual conditions or treatment. Let your provider know if they are excessive. information submitted for this request. Usually avoid combinations; use it only under special circumstances. HHS Vulnerability Disclosure, Help Yet many herbal supplements may interact with heart disease medicines. All rights reserved. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). Talk to your doctor about the possible risks of using this medication for your condition. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Alcohol can make the side effects from isosorbide worse. Selected from data included with permission and copyrighted by First Databank, Inc. eCollection 2021. Accessed Sept. 7, 2022. Are you looking for information on isosorbide dinitrate (Isordil) instead? Conclusions: Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Isosorbide is in a class of medications called vasodilators. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Do infrared saunas have any health benefits? To use the sharing features on this page, please enable JavaScript. Unless there is a specific reason you need the brand, the generic medication will be a better value. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Dated August 2017. Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. This should pass after a few days. Take isosorbide exactly as directed. Aspirin has an average rating of Garlic. Natural Medicines. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. St. John's wort. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. It is important that you follow the instructions your doctor gives to you about when to take your doses. This is so your doctor can check on your progress. Natural remedies for depression: Are they effective? Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. WebMD does not provide medical advice, diagnosis or treatment. Follow directions about how much medicine to take. What side effects can this medication cause? Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Does Alcohol Raise Your Blood Pressure? The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If tolerance is suspected during the use of transdermal patches they should be left off for 8-12 hours (usually overnight) in each 24 hours; in the case of modified-release tablets of isosorbide dinitrate (and . This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. https://naturalmedicines.therapeuticresearch.com. Contraindications: Isosorbide mononitrate should not be used in cases of acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or hypertrophic obstructive cardiomyopathy (HOCM), constrictive pericarditis, low cardiac filling pressures, aortic/mitral valve stenosis and diseases associated with a raised intra-cranial pressure e.g following a head trauma and including cerebral haemorrhage. The site is secure. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. My EKG showed Assess your symptoms online with our free symptom checker. Isosorbide tablets are also used with other medications to treat heart failure. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Accessed Sept. 7, 2022. With any medication, there are risks and benefits. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. If you suffer headaches when taking Isosorbide mononitrate, be patient. 72% of reviewers reported a positive effect, while 12% reported a negative effect. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. It is used to treat and prevent a wide range of different conditions. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Nitroglycerin has an average rating of [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). If you notice other effects not listed above, contact your doctor or pharmacist. In Canada - Call your doctor for medical advice about side effects. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. If you have any questions about this medicine ask your pharmacist. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Almost 70% of older adults use them. Does Viagra add to the risks of melanoma? It is unknown if this medication passes into breast milk. Aspirin relieves pain and inflammation and helps to thin the blood. Generic alternatives may be available. Would you like email updates of new search results? However, you should not flush this medication down the toilet. daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. We comply with the HONcode standard for trustworthy health information. Mayo Clinic; 2021. Some of these medicine interactions can be risky. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. https://naturalmedicines.therapeuticresearch.com. 8.0 out of 10 from a total of 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. A very serious allergic reaction to this drug is rare. This should pass after a few days. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. All rights reserved. Drug interactions may change how your medications work or increase your risk for serious side effects. Seek alternatives to the CYP3A4 substrate when possible. Does isosorbide mononitrate (Monoket) affect your kidneys? Diabetes treatment: Can cinnamon lower blood sugar? Never take extra doses or stop taking it suddenly unless your provider tells you to do so. Dated October 2016. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. It might help to keep the room cool and use a fan. It might help to take isosorbide mononitrate and dinitrate after meals. View more. This medicine is for you. Isosorbide mononitrate: isosorbide mononitrate. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Isosorbide mononitrate helps to prevent angina chest pain from developing. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. Talk to your doctor if you are using marijuana (cannabis). If you notice any other effects, check with your healthcare professional. Isosorbide mononitrate belongs to the group of medicines called nitrates. information is beneficial, we may combine your email and website usage information with Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Am J Ther. Which drugs or supplements interact with isosorbide mononitrate? Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Background: It does not work fast enough to relieve the pain of an angina attack that has already started. Accessed Sept. 7, 2022. Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. Accessed Sept. 7, 2022. Some products have ingredients that could worsen your heart failure. It is best not to drink alcohol while you are on isosorbide mononitrate. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. It is also important information to carry with you in case of emergencies. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. I would rather take the chance of a heart attack than have no quality of life. isosorbide mononitrate, along with These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). Headache is often a sign that this medication is working. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Accessed Sept. 7, 2022. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Upgrade to Patient Pro Medical Professional? Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. This content does not have an Arabic version. Copyright 2023 IBM Watson Health. and transmitted securely. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. Advertising revenue supports our not-for-profit mission. This branded product is no longer on the market. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Higher dosages are associated with stomach irritation and This is called a medicine interaction. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. This does not necessarily mean no interactions exist. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. US residents can call their local poison control center at 1-800-222-1222. View interaction reports for isosorbide mononitrate and the medicines listed below. Isosorbide may cause other side effects. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. The Swedish Multicentre Group. Keep this medication in the container it came in, tightly closed, and out of reach of children. St. Joseph 81 mg Aspirin Enteric Safety-Coated. All rights reserved. This content does not have an English version. Unable to load your collection due to an error, Unable to load your delegates due to an error. Do not share this medication with others. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. Patient does not provide medical advice, diagnosis or treatment. Isosorbide controls chest pain but does not cure coronary artery disease. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. If you have recently had a head injury or a heart attack. Botanical medicine A modern perspective. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Journals of the American College of Cardiology. What conditions does Isosorbide Mononitrate treat? [2] It is taken by mouth. Liperoti R, et al. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Dehydration in Buspar, how severe and when it was recovered? Never take more than the prescribed dose. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. official website and that any information you provide is encrypted
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